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Cecropin P1

Home/Antimicrobial Peptides/Cecropin P1
Cecropin P1Admin2020-08-25T03:07:54+00:00
Product Name Cecropin P1
Purity HPLC>95%
Description Cecropin P1 (SWLSKTAKKLENSAKKRISEGIAIAIQGGPR), a homolog of insect cecropins isolated from pig intestine, was thought to be the first mammalian antimicrobial peptide. Later studies showed that the peptide is produced by the intestinal parasitic nematode Ascaris suum. The 31 amino acid peptide is highly potent against Gram-negative bacteria but has a reduced activity against Gram-positive bacteria. A disruptive effect on bacterial membranes has been proposed as mechanism of antimicrobial activity.
Storage -20°C
References E.Gazit et al., Biochemistry, 34, 11479 (1995) J.-Y.Lee, Proc. Natl. Acad. Sci. USA, 86, 9159 (1989)
Molecular Weight 3338.90
Sequence (One-Letter Code) SWLSKTAKKLENSAKKRISEGIAIAIQGGPR
Sequence (Three-Letter Code) H-Ser-Trp-Leu-Ser-Lys-Thr-Ala-Lys-Lys-Leu-Glu-Asn-Ser-Ala-Lys-Lys-Arg-Ile-Ser-Glu-Gly-Ile-Ala-Ile-Ala-Ile-Gln-Gly-Gly-Pro-Arg-OH

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