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CRAMP-18

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CRAMP-18Admin2020-08-24T13:53:17+00:00
Product Name CRAMP-18
Purity HPLC>95%
Description CRAMP-18 is the anti-bacterial sequence derived from CRAMP, it possesses potent anti-bacterial activity against Gram-positive and Gram-negative bacterial strains with no haemolytic activity. As well as displaying direct anti-microbial activity, CRAMP-18 also binds to lipopolysaccharide (LPS) to neutralise LPS activity.
Storage -20°C
References Horibe et al (2013) Roles of cathelicidin-related antimicrobial peptide in murine osteoclastogenesis. Immunology 40(3) 344 PMID: 23826736 Wertenbruch et al (2015) The Anti-Microbial Peptide LL-37/CRAMP Is Elevated in Patients with Liver Diseases and Acts as a Protective Factor during Mouse Liver Injury. Digestion 91(4) 307 PMID: 25998843
Molecular Weight 2147.61
Sequence (One-Letter Code) GEKLKKIGQKIKNFFQKL-acid
Sequence (Three-Letter Code) H-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln-Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-OH

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