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Dermaseptin

Home/Antimicrobial Peptides/Dermaseptin
DermaseptinAdmin2020-08-25T03:12:22+00:00
Product Name Dermaseptin
Purity HPLC>95%
Description Dermaseptin was originally isolated from skin extracts of the South American arboreal frog, Phyllomedusa sauvagei. The strongly basic, nonhemolytic compound is the first vertebrate peptide that shows highly potent antimicrobial activity against pathogenic fungi at micromolar concentration. With a potentially amphiphatic α-helix structure, dermaseptin probably acts by membrane permeabilization.
Storage -20°C
References A.Mor et al., Biochemistry, 30, 8824 (1991)
Molecular Weight 3455.11
Sequence (One-Letter Code) ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
Sequence (Three-Letter Code) H-Ala-Leu-Trp-Lys-Thr-Met-Leu-Lys-Lys-Leu-Gly-Thr-Met-Ala-Leu-His-Ala-Gly-Lys-Ala-Ala-Leu-Gly-Ala-Ala-Ala-Asp-Thr-Ile-Ser-Gln-Gly-Thr-Gln-OH

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