| Product Name | Macropin 1 |
| Purity | HPLC>95% |
| Description | Macropin-1 (MAC-1) is an anti-microbial peptide (AMP) isolated from venom of the solitary bee Macropis fulvipes (Hymenoptera: Melittidae). MAC-1 has activity against both Gram-positive and Gram-negative bacteria, including drug-resistant strains. MAC-1 can inhibit biofilm formation in Staphylococcus aureus and Pseudomonas aeruginosa and also exhibits anti-fungal activity. MAC-1 has little to no haemolytic activity against human cells at microbiologically effective concentrations. |
| Storage | -20°C |
| References | Ko et al (2017) Macropis fulvipes Venom component Macropin Exerts its Antibacterial and Anti-Biofilm Properties by Damaging the Plasma Membranes of Drug Resistant Bacteria. Sci. Rep. 7(1) PMID: 29185466 |
| Molecular Weight | 1416.86 |
| Sequence (One-Letter Code) | GFGMALKLLKKVL-amide |
| Sequence (Three-Letter Code) | H-Gly-Phe-Gly-Met-Ala-Leu-Lys-Leu-Leu-Lys-Lys-Val-Leu-NH2 |
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