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Pap12-6

Home/Antimicrobial Peptides/Pap12-6
Pap12-6Admin2020-08-25T02:04:45+00:00
Product Name Pap12-6
Purity HPLC>95%
Description Broad-spectrum antibacterial, active against multidrug-resistant Gram-negative bacteria. Acts though permeabilizing the bacterial membrane and also shows anti-inflammatory activity via a TLR4-mediated NF-κB signaling pathway. Significantly improves survival in a mouse sepsis model.
Storage -20°C
References Kim et al (2019) Development of a novel short 12-meric papiliocin-derived peptide that is effective against Gram-negative sepsis. Sci. Rep. 9 3817 PMID: 30846839
Molecular Weight 1644.1
Sequence (One-Letter Code) RWKIFKKVVKKW-amide
Sequence (Three-Letter Code) H-Arg-Trp-Lys-Ile-Phe-Lys-Lys-Val-Val-Lys-Lys-Trp-NH2

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