Porcine myeloid antimicrobial peptide-23 (PMAP-23) is a host defense peptide that belongs to cathelicidins. It has potent activity against Gram-negative and Gram-positive bacteria1, and displays strong antifungal activity against yeast and mold2-3. It is not toxic to eukaryotic cells up to concentrations 100 times higher than those needed for bactericidal activity.
1. Park K et al., Biochem. Biophys. Res. Commun. 290(1) 204-212 (2002) 2. Edwin J.A.V et al., Protein Pept Lett. 24(7),609-616 (2017) 3. Lee D.G et al., Biochem. Biophys. Res. Commun ,282 (2) 570-74 (2001)
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Arg - Ile - Ile - Asp - Leu - Leu - Trp - Arg - Val - Arg - Arg - Pro - Gln - Lys - Pro - Lys - Phe - Val - Thr - Val - Trp - Val - Arg - OH