SMAP -18 is 18-residue peptide amide truncated form of SMAP-29. Sheep myeloid antimicrobial peptide-29 (SMAP-29) displays extremely high antimicrobial activity against Pseudomonas strains, other gram-negative bacteria, and multidrug-resistant pathogens1. SMAP-18 displays much higher cell selectivity as compared to parental SMAP-29 because of their decreased hemolytic activity and retained antimicrobial activity2.
1. Saiman, L. et al. Antimicrob. Ag. Chemother. 45, 2838 (2001) 2. Jacob B, et al., Amino Acids 46(1),187-98 (2014)
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Arg - Gly - Leu - Arg - Arg - Leu - Gly - Arg - Lys - Ile - Ala - His - Gly - Val - Lys - Lys - Tyr - Gly - NH2