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Amyloid β-Protein (1-14)

Home/Beta Amyloid Peptides/Amyloid β-Protein (1-14)
Amyloid β-Protein (1-14)Admin2020-12-18T12:33:39+00:00
Product Name Amyloid β-Protein (1-14)
Purity HPLC>95%
Description The N-terminal Aβ fragments Aβ1-14, Aβ1-15, and Aβ1-16 are elevated in cell media and in CSF in response to γ-secretase inhibitor treatment. The presence of these small peptides is consistent with a catabolic amyloid precursor protein cleavage pathway by β- followed by α-secretase. It has been shown that Aβ1-14, Aβ1-15, and Aβ1-16 increase dose-dependently in response to γ-secretase inhibitor treatment while Aβ1-42 levels are unchanged.
Storage -20°C
References E.Portelius et al., Neurodegener. Dis., 10, 138 (2012) E.Portelius et al., Curr. Pharm. Des., 17, 2594 (2011) E.Portelius et al., Alzheimer Res. Ther., 2, 7 (2010)
Molecular Weight 1698.73
Sequence (One-Letter Code) DAEFRHDSGYEVHH
Sequence (Three-Letter Code) H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-OH

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