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Amyloid β-Protein (1-6) amide

Home/Beta Amyloid Peptides/Amyloid β-Protein (1-6) amide
Amyloid β-Protein (1-6) amideAdmin2020-12-18T12:35:32+00:00
Product Name Amyloid β-Protein (1-6) amide
Purity HPLC>95%
Description Experiments using sub-peptides of Aβ42 revealed that the epitope identified by the antibody A8, as described by Ying and coworkers, lies within the 1-6 region of Aβ. The antibody displays high affinity for soluble Aβ42 oligomers in the molecular weight range of 16.5-25 kDa, and detected target antigen in brain sections from senescence-accelerated SAMP 8 mice. Amidated or acetylated and amidated forms of the sequence were used for example for quantitative structure retention relationships (QSRR) experiments. The latter could allow prediction of reversed-phase high-performance liquid chromatography (HPLC) retention of peptides, as reported by Kaliszan and coworkers.
Storage -20°C
References Z.Ying et al., Hybridoma, 28, 349 (2009) R.Kaliszan et al., Proteomics, 5, 409 (2005)
Molecular Weight 772.81
Sequence (One-Letter Code) DAEFRH-NH₂
Sequence (Three-Letter Code) H-Asp-Ala-Glu-Phe-Arg-His-NH₂

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