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Adeno-Associated Virus Epitope 2 (AAV2)

Home/Catalog peptide/Adeno-Associated Virus Epitope 2 (AAV2)
Adeno-Associated Virus Epitope 2 (AAV2)Admin2021-01-15T04:51:01+00:00
Product Name Adeno-Associated Virus Epitope 2 (AAV2)
Purity HPLC>95%
Description This peptide is a capsid-derived immunodominant adeno-associated virus 2 (AAV2), cd8t cell epitope. The hepatotoxicity of systemic inoculation of AAV2 in hemophilia patients observed in a clinical trial was due to the killing of vector-transduced liver cells by capsid-specific T cells.
Storage -20°C
References Murphy, S. et al. Blood (ASH Annual Meeting Abstracts), 108 (2006), Mingozzi, F. et al. Nature Medicine 10.1038/nm1549 (2007), Wang, L. et al. Therapy. 18, 185 (2007).
Molecular Weight 1053.2
Sequence (One-Letter Code) VPQYGYLTL
Sequence (Three-Letter Code) H - Val - Pro - Gln - Tyr - Gly - Tyr - Leu - Thr - Leu - OH

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