This peptide is derived from amino acid residues 4 to 18 of the atrial natriuretic peptide (ANP). It has been used as a model cysteine containing peptide in quantitative mass spectroscopic analysis. This fragment is also related to C-ANP (4-23); (Des-Gln18,des-Ser19,des-Gly20,22,des-Leu21), which is completely selective in discriminating rat C-AMP receptors.
Xu, G. et. Al. Analytical Chem. 77, 2437 (2005); Rutherford, R. et al. J. Biol. Chem. 266, 5819 (1991).
Sequence (One-Letter Code)
RSSCFGGRIDRIGAC-NH2 (Disulfide bridge 4-15)
Sequence (Three-Letter Code)
H - Arg - Ser - Ser - Cys - Phe - Gly - Gly - Arg - Ile - Asp - Arg - Ile - Gly - Ala - Cys - NH2 (Disulfide bridge 4 - 15)