This is a myristoylated form of Autocamtide-2 related inhibitory peptide (AIP), a highly effective specific substrate competitive inhibitor of calmodulin-dependent protein kinase ll (CaMKII). AIP is derived from Autocamtide-2, the substrate of CaMKII, and the phosphorylation site of Thr-9 is replaced by Ala
Ishida, A. et al. J Biol Chem 270, 2163 (1995); Ji, Y. et al. J Biol Chem 278, 25063 (2003).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
Myr - Lys - Lys - Ala - Leu - Arg - Arg - Gln - Glu - Ala - Val - Asp - Ala - Leu - OH