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Charybdotoxin

Home/Catalog peptide/Charybdotoxin
CharybdotoxinAdmin2021-01-07T06:30:51+00:00
Product Name Charybdotoxin
Purity HPLC>95%
Description Charybdotoxin (ChTX) is a calcium-activated K+ channel blocker. It depolarizes peripheral blood T lymphocytes and prevents their proliferation induced by mitogen. ChTX is a highly basic peptide, isolated from the venom of scorpions
Storage -20°C
References Ref: Leonard, R. et al. Proc. Natl. Acad. Sci. USA 89, 10094 (1992); Gimenez-Gallego, Proc. Natl. Acad. Sci. USA 85, 3329 (1988). Sugg, E. et al. J. Biol. Chem. 265, 18745 (1990).
Molecular Weight 4296
Sequence (One-Letter Code) Pyr-FTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS (Disulfide bridge: 7-28, 13-33 and 17-35)
Sequence (Three-Letter Code) Pyr - Phe - Thr - Asn - Val - Ser - Cys - Thr - Thr - Ser - Lys - Glu - Cys - Trp - Ser - Val - Cys - Gln - Arg - Leu - His - Asn - Thr - Ser - Arg - Gly - Lys - Cys - Met - Asn - Lys - Lys - Cys - Arg - Cys - Tyr - Ser - OH (Disulfide bridge: 7 - 28, 13 - 33 and 17 - 35)

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