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Cls Substrate, C2 (Abz/Dnp)

Home/Catalog peptide/Cls Substrate, C2 (Abz/Dnp)
Cls Substrate, C2 (Abz/Dnp)Admin2021-01-08T01:47:41+00:00
Product Name Cls Substrate, C2 (Abz/Dnp)
Purity HPLC>95%
Description This peptide is the second complement component (C2), the physiological substrate of the proenzyme Cls, the first complement component. The complement system is a central component of host defense, but it can also cause inflammation in pathological conditions. The C1s protease of the C1 complex initiates the host defense pathway. The peptide uses 2Abz/Dnp-FRET pair to quantitatively analyze complement enzyme activity
Storage -20°C
References Kerr, F. et al. J. Biol. Chem. 280, 39510 (2005), S. Nagasawa, and R. Stroud PNAS 74, 2998 (1977).
Molecular Weight 1326.5
Sequence (One-Letter Code) 2Abz-SLGRKIQIK(Dnp)-NH2
Sequence (Three-Letter Code) 2Abz - Ser - Leu - Gly - Arg - Lys - Ile - Gln - Ile - Lys(Dnp) - NH2

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