This is the 16 amino acid region of Antennapedia peptide (Penetratin) synthesized with an activated cysteine residue C(Npys), wherein Npys is 3-Nitro-2-pyridinesulfenyl group is used for activating S of cysteine and for rapid reaction when a thiol group is introduced. This kind of modification has been used to render this peptide as a carrier peptide applicable in conjugation studies, especially when studying attachment of peptide-like molecules to carriers.
Hodoniczky J. et al. Pep Sci. 90(5):595-603(2008).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - C(Npys)Arg - Gln - Ile - Lys - Ile - Trp - Phe - Gln - Asn - Arg - Arg - Met - Lys - Trp - Lys - Lys - NH2