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Exendin 4, FAM-labeled

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Exendin 4, FAM-labeledAdmin2021-01-07T07:10:16+00:00
Product Name Exendin 4, FAM-labeled
Purity HPLC>95%
Description This full-length exendin4 amide peptide is labeled with a fluorescent dye (FAM) at its N-terminus, Abs/Em=494/519nm. The glucagon-like peptide 1 (GLP-1) receptor agonist Exendin-4 induces insulin release after eating. Exendin-4 shares 53% homology with GLP-1. Exendin-4 is derived from Gila monster, Heloderma suspectim. Its half-life in plasma is longer than GLP-1, so it is a more effective insulinotropic agent
Storage -20°C
References Eng, J. et al. J Biol Chem 267, 7402 (1992) Greig, NH. et al. Diabetolog 42, 45 (1999) Göke R. et al. J Biol Chem 268, 19650 (1993)
Molecular Weight 4545
Sequence (One-Letter Code) FAM-HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
Sequence (Three-Letter Code) FAM - His - Gly - Glu - Gly - Thr - Phe - Thr - Ser - Asp - Leu - Ser - Lys - Gln - Met - Glu - Glu - Glu - Ala - Val - Arg - Leu - Phe - Ile - Glu - Trp - Leu - Lys - Asn - Gly - Gly - Pro - Ser - Ser - Gly - Ala - Pro - Pro - Pro - Ser - NH2

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