| Product Name | Gastrin-1, rat |
| Purity | HPLC>95% |
| Description | Like human gastrin-1 "minigastrin", rat gastrin-1 "minigastrin" contains 17 amino acids, but unlike human gastrin, there are 3 amino acids at the C-terminal. The secretion of gastrin is caused by food intake and causes the release of gastric acid. Gastrin is mainly synthesized by a biologically active substance n in the gastric mucosa. Both gastrin-17 and gastrin-34 are carboxy amidated and partially tyrosine sulfated. The binding of gastrin to CCK2/gastrin receptor requires carboxy amidation, but binding to the receptor does not require sulfation. |
| Storage | -20°C |
| References | Reeve, JR. et al. Peptides 2, 453 (1981) Schaffer, MH. et al. Peptides 3, 693 (1982), doi: 10.1016/0196-9781(82)90172-3 Niederle, B. Wien Klin Wochenschr 119, 561 (2007), doi: 10.1007/s00508-007-0897-x. O’Connor A. et. al. Digestive Dis 32, 186 (2014), doi: 10.1159/000357848 Dockray, G. et.al. Pflügers Archiv 449,344 (2005) Bundgaard, JR. et al. J Biol Chem 272, 21700 (1997), doi: 10.1074/jbc.272.35.21700 Yakabi, K. et al. World J Gastroenterol 14, 6334 (2008), doi: 10.3748/wjg.14.6334 |
| Molecular Weight | 2126.3 |
| Sequence (One-Letter Code) | Pyr-RPPMEEEEEAYGWMDF-NH2 |
| Sequence (Three-Letter Code) | Pyr - Arg - Pro - Pro - Met - Glu - Glu - Glu - Glu - Glu - Ala - Tyr - Gly - Trp - Met - Asp - Phe - NH2 |
Gastrin-1, ratAdmin2021-01-08T02:47:10+00:00
