Gastrin releasing peptide (Gastrin releasing peptide, referred to as Gastrin releasing peptide) is a 27-amino acid peptide isolated from the intestine, which can stimulate the release of gastrin. It shares the same C-terminal decapeptide with bombesin. Source. Gastrin releasing peptide is an important growth regulator in the development of lung epithelium. It is used as a tumor marker for the diagnosis of small cell lung cancer because it is known to be produced by these cancer cells.
Kamata, K. et al. Nephrol Dialysis Transplant 11, 1267 (1996), doi: 10.1093/ndt/11.7.1267 Taché, Y. et al. Gastroenterol 81, 298 (1981) Siegfried, J. et al. J Biol Chem 269, 8596 (1994) Patel, O. et al. Biochem Pharmacol 68, 2129 (2004), doi: 10.1016/j.bcp.2004.08.009 Niederle, B. Wien Klin Wochenschr 119, 561 (2007), doi: 10.1007/s00508-007-0897-x.
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Val - Pro - Leu - Pro - Ala - Gly - Gly - Gly - Thr - Val - Leu - Thr - Lys - Met - Tyr - Pro - Arg - Gly - Asn - His - Trp - Ala - Val - Gly - His - Leu - Met - NH2