This GRG-containing peptide is a 1 to 20 amino acid fragment of histone 4. It is the substrate of human protein arginine methyltransferase 7 (PRMT7), which is a type II methyltransferase that can produce symmetric dimethylarginine (sDMA) modifications in proteins.
Lee, J. et al. J. Biol. Chem. 280, 3656 (2005).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ser - Gly - Arg - Gly - Lys - Gly - Gly - Lys - Gly - Leu - Gly - Lys - Gly - Gly - Ala - Lys - Arg - His - Arg - Lys - NH2