The peptide consists of 1-23 amino acids of histone H4 and is connected to the C-terminus of biotinylated lysine through a GSGS linker. It is used as a substrate for histone acetyltransferase (HAT) analysis. Biotinylation allows peptides to be captured by streptavidin or sepharose beads.
Ait-Si-Ali, A. et al. Nucleic Acids Res 26, 3869 (1998).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ser - Gly - Arg - Gly - Lys - Gly - Gly - Lys - Gly - Leu - Gly - Lys - Gly - Gly - Ala - Lys - Arg - His - Arg - Lys - Val - Leu - Arg - Gly - Ser - Gly - Ser - Lys(Biotin) - OH