This is one of the cell penetrating peptides (CPPs) extracted from residues 48-60 of the human immunodeficiency virus (HIV)-1tat protein. It is used to transport exogenous macromolecules into cells in a non-destructive manner.
Dennison, S.R. et al. Biochem. and Biophy. Res. Comm. 363, 178 (2007); Futaki, S. Advanced Drug Delivery Rev. 57, 547 (2005)
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - Pro - Pro - Gln - OH