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[Lys(Ac)12]-Histone H4 (1-20), H4K12(Ac)

Home/Catalog peptide/[Lys(Ac)12]-Histone H4 (1-20), H4K12(Ac)
[Lys(Ac)12]-Histone H4 (1-20), H4K12(Ac)Admin2021-01-12T12:15:17+00:00
Product Name [Lys(Ac)12]-Histone H4 (1-20), H4K12(Ac)
Purity HPLC>95%
Description This peptide is histone 4 acetylation at lysine 12. Based on genome-wide localization studies, it was found that the peptide occupies the promoter region at the transcription start site, especially related to specific promoters, which may drive high-level mRNA transcripts stored in mature sperm. These observations led to the hypothesis that H4K12Ac may be one of the epigenetic markers of developmental genes.
Storage -20°C
References 1, Borra, MT. et al. Biochem. 43, 9877 (2004) 2, Paradowska AS. et al. Epigen, 7(9):1057-70 (2012).
Molecular Weight 2034.4
Sequence (One-Letter Code) SGRGKGGKGLG-K(Ac)-GGAKRHRK
Sequence (Three-Letter Code) H - Ser - Gly - Arg - Gly - Lys - Gly - Gly - Lys - Gly - Leu - Gly - Lys(Ac) - Gly - Gly - Ala - Lys - Arg - His - Arg - Lys - OH

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