The amino acid residues of lys382-379 were inhibited. It is biotinylated at its N-terminal via a 6-carbon LC linker. The function of activated p53 is to induce cell cycle arrest and apoptosis in response to signals such as DNA damage. Acetylation of p53 can reduce the ubiquitination of MDM2 and prolong the half-life of p53 in vivo.
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
Biotin - LC - Lys - Lys - Gly - Gln - Ser - Thr - Ser - Arg - His - Lys - Lys(Ac) - Leu - Met - Phe - Lys - Thr - Glu - Gly - OH