The peptide sequence is present in residues 1 to 21 of histone H3K9 (Ac). H3K9(Ac) is highly located in the 5'region of the transcription start site of human genes. The location of H3K9(Ac) in the 5'region of human gene transcription activity indicates that this peptide is essential for transcription initiation and extension.
Midorikawa, K. et al. Biochem Biophys Res Commun 333, 1073 (2005).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Arg - Thr - Lys - Gln - Thr - Ala - Arg - Lys(Ac) - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys - Gln - Leu - Ala - OH