This is the 9-position monomethyllysine of the 1-21 amino acid histone H3 peptide. The characteristic of histone methylation is the enrichment near the transcription start point. This peptide has been used as a control peptide in TR-FRET analysis to identify histone lysine demethylase inhibitors.
1, Tian Y. et al. PLOS One. 6(11):e27770 (2011) 2, Yu V. et al. J Biomol Screen. 1791):27-38 (2011).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Arg - Thr - Lys - Gln - Thr - Ala - Arg - Lys(Me1) - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys - Gln - Leu - Ala - OH