The peptide is histone H3 amino acid residues 1-21. Lysine 9 is dimethylated with a C-terminal GG linker, followed by biotinylated lysine. The dimethylation of histone H3 on lysine 9 is dynamically and gender-differentially regulated during the prophase of meiosis. When the peptide purity is greater than 95%, the peptide is dissolved in distilled water at a concentration of 1 mg/ml, and lyophilized again into a powder form.
Tachibana, M. et al. Embo J 26, 14 (2007).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Arg - Thr - Lys - Gln - Thr - Ala - Arg - Lys(Me2) - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys - Gln - Leu - Ala - Gly - Gly - Lys(Biotin) - NH2