| Product Name | [Lys(Me3)36]-Histone H3 (21-44)-GK(Biotin), H3K36(Me3), biotin-labeled |
| Purity | HPLC>95% |
| Description | This is histone 3 lysine 36 dimethylated peptide. This peptide has been shown to form a histone deacetylase complex with nucleosomes and inhibit transcription. In addition, due to its epigenetic suppression marker, it allows the demethylation of JMJD5, a member of the Jumonji C domain family, which acts as a transcriptional activator by inhibiting HDAC and regulates cell cycle proliferation. |
| Storage | -20°C |
| References | 1, Luco RF. et al. Science, 327:996-1000 (2010) 2, Carrozza MJ. et al. Cell, 123:581-592 (2005). |
| Molecular Weight | 2959.5 |
| Sequence (One-Letter Code) | ATKAARKSAPATGGV-K(Me3)-KPHRYRPG-GK(Biotin) |
| Sequence (Three-Letter Code) | H - Ala - Thr - Lys - Ala - Ala - Arg - Lys - Ser - Ala - Pro - Ala - Thr - Gly - Gly - Val - Lys(Me3) - Lys - Pro - His - Arg - Tyr - Arg - Pro - Gly - Gly - Lys(Biotin) - OH |
[Lys(Me3)36]-Histone H3 (21-44)-GK(Biotin), H3K36(Me3), biotin-labeledAdmin2021-01-12T06:57:41+00:00
