This peptide is a synthetic peptide corresponding to amino acids 1-21 of human histone H3. Trimethylated with the C-terminal Gly-Gly linker at Lys-4, followed by biotinylated lysine. The trimethylation of histone H3 at lysine 4[H3K4(Me3)] reveals the cell status and lineage potential through differentiation of genes that are expressed, ready to be expressed, or suppressed. H3K4 (Me3) also marked the imprint control area
Midorikawa, K. et al. Biochem Biophys Res Commun 333, 1073 (2005).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Arg - Thr - Lys(Me3) - Gln - Thr - Ala - Arg - Lys - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys - Gln - Leu - Ala - Gly - Gly - Lys(Biotin) - NH2