This synthetic peptide corresponds to 1-25 amino acids of human histone H3. It is trimethylated at 4 lysine. The trimethylation of histone H3 at lysine 4[H3K4(Me3)] reveals the cell status and lineage potential through differentiation of genes that are expressed, ready to be expressed, or suppressed. H3K4 (Me3) also marked the imprint control area.
Midorikawa, K. et al. Biochem Biophys Res Commun 333, 1073 (2005).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Arg - Thr - Lys(Me3) - Gln - Thr - Ala - Arg - Lys - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys - Gln - Leu - Ala - Thr - Lys - Ala - Ala - NH2