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MUC1, tandem repeat fragment

Home/Catalog peptide/MUC1, tandem repeat fragment
MUC1, tandem repeat fragmentAdmin2021-01-06T06:12:28+00:00
Product Name MUC1, tandem repeat fragment
Purity HPLC>95%
Description This sequence is the hallmark of MUC1 mucin. MUC1 is a highly glycosylated type I transmembrane glycoprotein with a unique extracellular domain consisting of a variable number of tandem repeats (VNTR) of this 20 amino acid peptide It is overexpressed on the cell surface of many human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma, making MUC1 broadly applicable target for immunotherapeutic strategies
Storage -20°C
References Brossart, P. et al. Blood 93, 4309 (1999); Wajchman, H. et al. Cancer Res 64, 1171 (2004)
Molecular Weight 1887
Sequence (One-Letter Code) PDTRPAPGSTAPPAHGVTSA
Sequence (Three-Letter Code) Pro - Asp - Thr - Arg - Pro - Ala - Pro - Gly - Ser - Thr - Ala - Pro - Pro - Ala - His - Gly - Val - Thr - Ser - Ala

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