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Neural-Cadherin (76-85) amide (chicken)

Home/Catalog peptide/Neural-Cadherin (76-85) amide (chicken)
Neural-Cadherin (76-85) amide (chicken)Admin2021-01-17T11:30:56+00:00
Product Name Neural-Cadherin (76-85) amide (chicken)
Purity HPLC>95%
Description The decapeptide is located in the first extracellular domain (EC1) of N-cadherin. It inhibits cadherin-mediated cell adhesion, the tightening of mouse embryos at the eight-cell stage, and the growth of rat neurites on astrocytes. In the presence of this peptide, the Ca 2+ dependent cell aggregation of bovine brain microvascular endothelial cells is prevented. Putative applications in establishing a pathway for paracellular drug delivery across the blood-brain barrier have been proposed.
Storage -20°C
References D.Pal et al., Brain Res., 747, 103 (1997)O.W.Blaschuk et al., Dev. Biol., 139, 227 (1990)
Molecular Weight 1050.19
Sequence (One-Letter Code) LRAHAVDVNG-NH₂
Sequence (Three-Letter Code) H-Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-NH₂

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