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Pep-1-Cysteamine

Home/Catalog peptide/Pep-1-Cysteamine
Pep-1-CysteamineAdmin2021-01-06T09:43:10+00:00
Product Name Pep-1-Cysteamine
Purity HPLC>95%
Description Pep-1 is a synthetic cell penetrating peptides (CPPs) that has successfully delivered a variety of proteins and other biopharmaceutical macromolecules to cells in a non-destructive manner. It is a kind of CPP with primary amphiphilicity (that is, amphiphilicity produced by the amino acid sequence itself, not caused by the folding structure), which includes a so-called "hydrophobic" domain rich in tryptophan, and one from SV40 ( Simian virus 40) the hydrophilic domain derived from the NLS (nuclear localization signal) of the large T antigen, and the spacer between them. The cysteamine group is present at the C-terminus. The presence of the cysteamine group at the C-terminus plays a crucial role in the efficiency of cargo entering the cell.
Storage -20°C
References Henriques, S. et al. FEBS Letters Vol. 579, 4498 (2005).
Molecular Weight 2949.5
Sequence (One-Letter Code) Ac-KETWWETWWTEWSQPKKKRKV-cysteamine
Sequence (Three-Letter Code) Ac - Lys - Glu - Thr - Trp - Trp - Glu - Thr - Trp - Trp - Thr - Glu - Trp - Ser - Gln - Pro - Lys - Lys - Lys - Arg - Lys - Val - cysteamine

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