This is the 178-191 amino acid fragment of protein lipoprotein (PLP), which is one of the immunoproinflammatory epitopes in SJL mice. PLP 178 to 191 peptides were compared with another encephalitic peptide 139 to 151. Plp178-191 induced diseases occur earlier, but their incidence, severity and histological features cannot be distinguished.
Greer, J. et al. J. Immunol. 149, 783 (1992); Greer, J. et al. Neurochem. Res. 22, 541-(1997); Bischof, F. et al. J. Immunol. 173, 600 (2004).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Asn - Thr - Trp - Thr - Thr - Cys - Gln - Ser - Ile - Ala - Phe - Pro - Ser - Lys - OH