Tat-Glur23Y is a control peptide. A synthetic peptide containing tyrosine residues (Tat-Glur23Y) blocks the phosphorylation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor endocytosis. However, the scrambled version has no blocking properties. Previous studies have shown that Tat-Glur23Y, crambled increases the stress level of mice, while Tat-Glur23Y can reduce stress when administered
Dalton, G. et al. Neuropsychopharma. 33, 2416 (2008); Kim, J. et al. PNAS 104, 20955 (2007).