This sequence is an N-ethylmaleimide sensitive factor (NSF) peptide, which is connected to the 11 amino acid cell-permeable human immunodeficiency virus (HIV) transactivation regulatory protein (TAT) through the Gly-Gly-Gly spacer Structural domain. This peptide contains the NSF domain from 222 to 243, which is directly the amino terminus of the Walker A motif of the NSF D1 domain. Atp enzyme analysis shows that TAT-NSF222 inhibits NSF-ATPase activity
Matsushita, K. et al. Mol. Pharmacol. 67,1137 (2005).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Tyr - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - Gly - Gly - Gly - Leu - Asp - Lys - Glu - Phe - Asn - Ser - Ile - Phe - Arg - Arg - Ala - Phe - Ala - Ser - Arg - Val - Phe - Pro - Pro - Glu - OH