Skip to content
Best Biochem | Custom Peptide | Protein | Antibody | RNA oligos | Inhibitor Logo
  • Home
  • About us
  • Custom Services
    • Custom Peptide Synthesis
      • Peptide Modification
      • Peptide Array
      • Peptide Library
    • Custom Antibody Services
      • Monoclonal Antibody Services
      • Polyclonal Antibody Services
    • Custom DNA/RNA Synthesis
      • siRNA
      • miRNA
    • Analytical Services
  • Products
    • Research Peptides
      • Beta Amyloid Peptides
      • Amylins (IAPP) Peptide Fragments
      • Antimicrobial Peptides
      • Catalog peptide
    • Antibodies
      • Primary Antibodies
      • Secondary Antibodies
    • API and Impurity
    • Inhibitor and Agonist
  • Technology transfer
  • Support
    • FAQ’s
  • CN/EN
  • Home
  • About us
  • Custom Services
    • Custom Peptide Synthesis
      • Peptide Modification
      • Peptide Array
      • Peptide Library
    • Custom Antibody Services
      • Monoclonal Antibody Services
      • Polyclonal Antibody Services
    • Custom DNA/RNA Synthesis
      • siRNA
      • miRNA
    • Analytical Services
  • Products
    • Research Peptides
      • Beta Amyloid Peptides
      • Amylins (IAPP) Peptide Fragments
      • Antimicrobial Peptides
      • Catalog peptide
    • Antibodies
      • Primary Antibodies
      • Secondary Antibodies
    • API and Impurity
    • Inhibitor and Agonist
  • Technology transfer
  • Support
    • FAQ’s
  • CN/EN

Tau (260–267) Light

Home/Catalog peptide/Tau (260–267) Light
Tau (260–267) LightAdmin2021-01-17T07:30:52+00:00
Product Name Tau (260–267) Light
Purity HPLC>95%
Description Tubulin-related unit (tau) residues 260-267. This region represents the death-associated protein kinase 1 (DAPK1) binding domain in the tau microtubule repeat domain (R). DAPK1 phosphorylates tau on ser262 in ischemic brain injury. The peptide can block the interaction between DAPK1 and tau and reduce the level of phosphorylation of ser262, so it may have therapeutic benefits. Tau is a phosphoprotein involved in the assembly and stability of microtubules (MT) and brain development. Tau is phosphorylated by a variety of protein kinases at multiple sites, including cyclic AMP-dependent protein kinase and type 1 casein kinase. Tau phosphorylation causes tau to change shape, thereby negatively modulating its ability to stimulate MT assembly. The malfunctioning tau protein contributes to the structural core of the paired helical filaments (PHF) that make up the neurofibrillary tangles (NFT). NFT is usually observed in neurodegenerative diseases such as Alzheimer's disease and other diseases
Storage -20°C
References Šimić et al (2016) Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies. Biomolecules 6(1) 6 PMID: 26751493 Gendreau and Hall (2013) Tangles, Toxicity, and Tau Secretion in AD – New Approaches to a Vexing Problem. Front. Neurol. 4 PMID: 24151487
Molecular Weight 860.5
Sequence (One-Letter Code) IGSTENLK
Sequence (Three-Letter Code) Ile-Gly-Ser-Thr-Glu-Asn-Leu-Lys-OH

Other Products

  • Research peptides
  • Antibodies
  • Drug for research
  • Inhibitor and agonist

Related Products

Beta-Amyloid (1-42), Human

Beta-Amyloid (1-42), FAM-labeled, Human

Amylin (1-37), rat, mouse

Amylin (1-37), human, amide

rCRAMP

LL-37 Citrulline

β-Defensin 2 (human)

Contact us
  • Skype: elisa.qiujx
  • elisa@bestbiochem.com
  • WeChat

  • QQ: 1652852700

CUSTOM SERVICES

  • Peptide Synthesis
  • Antibody Production
  • DNA/RNA Synthesis

CHARACTERISTIC PRODUCTS

  • Research Peptide
  • Antibody
  • API and Impurity
  • Inhibitor and Agonist

Contact Info

No. 199 Huayuan Dong Road, Wuzhong Qu,Suzhou Shi, Jiangsu Sheng, China

Phone: +86 18021243762 (same as Wechat)

Email: info@bestbiochem.com

Web: bestbiochem.com

Recent Tweets

Copyright 2012 - 2017 BestBiochem | All Rights Reserved
LinkedInFacebookTwitter
Go to Top