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WP9QY, TNF-alpha Antagonist

Home/Catalog peptide/WP9QY, TNF-alpha Antagonist
WP9QY, TNF-alpha AntagonistAdmin2021-01-05T06:11:28+00:00
Product Name WP9QY, TNF-alpha Antagonist
Purity HPLC>95%
Description This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.
Storage -20°C
References Saito, H. et al. Arthritis Rheum. 56, 1164 (2007).
Molecular Weight 1226.4
Sequence (One-Letter Code) YCWSQYLCY (Disulfide bridge: 2-8)
Sequence (Three-Letter Code) H - Tyr - Cys - Trp - Ser - Gln - Tyr - Leu - Cys - Tyr - OH (Disulfide bridge: 2 - 8)

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