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43Gap 26, Connexin Mimetic

Home/Catalog peptide/43Gap 26, Connexin Mimetic
43Gap 26, Connexin MimeticAdmin2021-01-06T07:09:04+00:00
Product Name 43Gap 26, Connexin Mimetic
Purity HPLC>95%
Description This Gap 26 peptide is derived from the first extracellular loop sequence of connexin (Cx) 43. This short mimetic peptide reversibly inhibits the gap junction-dependent propagation of Ca2+ waves between tracheal airway epithelial cells. Connexins, or gap junctions, are a family of structurally-related transmembrane proteins. Gap junctions contain channels that allow the passage of ions and small molecules between adjacent cells molecules. Calcium and inositol phosphates are among the second messengers that can pass through gap junction channels.
Storage -20°C
References Boitano, S. and H. Evans Am. J. Physiol. Lung Cell Mol. Physiol. 279, L623 (2000).
Molecular Weight 1550.8
Sequence (One-Letter Code) VCYDKSFPISHVR
Sequence (Three-Letter Code) H - Val - Cys - Tyr - Asp - Lys - Ser - Phe - Pro - Ile - Ser - His - Val - Arg - OH

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