This peptide is from amino acid residues 1 to 21 of histone H4. It is monomethylated at Arg3, using acetylated N-terminal and C-terminal GG linkers, followed by biotinylated lysine. The methylation of histone H4 at Arg3 is an important step in transcriptional activation and allows subsequent acetylation of the H4 tail by p300. When the peptide purity is greater than 90%, the peptide is dissolved in distilled water at a concentration of 1 mg/ml, and lyophilized again into powder
Wang, H. et al. Science 293, 853 (2001).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
Ac - Ser - Gly - Arg(Me1) - Gly - Lys - Gly - Gly - Lys - Gly - Leu - Gly - Lys - Gly - Gly - Ala - Lys - Arg - His - Arg - Lys - Val - Gly - Gly - Lys(Biotin) - OH