This is a myristoylated form of Autocamtide-3 derived inhibitory peptide (AC3-I). It is a highly specific inhibitor of calmodulin-dependent protein kinase ll (CaMKII) and is resistant to proteolysis. Replace the base alanine-3 with phosphorylase 3.
Chen, HX. et al. J Neurophysiol 85, 1368 (2001).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
Myr - Lys - Lys - Ala - Leu - His - Arg - Gln - Glu - Ala - Val - Asp - Ala - Leu - OH