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Caspase 1 (ICE) Substrate 3f, fluorogenic

Home/Catalog peptide/Caspase 1 (ICE) Substrate 3f, fluorogenic
Caspase 1 (ICE) Substrate 3f, fluorogenicAdmin2021-01-05T08:29:21+00:00
Product Name Caspase 1 (ICE) Substrate 3f, fluorogenic
Purity HPLC>95%
Description AFC (7-amino-4-trifluoromethylcoumarin)-derived caspase substrates are widely used for the fluorimetric detection of various caspase activities. Cleavage of AFC peptides by caspases generate strongly fluorescent AFC that is monitored fluorimetrically at 500-510 nm with excitation of 370-390 nm.
Storage -20°C
References 1, Gurtu V, et al. Anal Biochem 251, 98-102 (1997).; 2. Martins LM, et al. J Biol Chem 272, 7421-30 (1997).; 3. Deveraux QL, et al. Nature 388, 300-4 (1997).; 4. Xiang J, et al. Proc Natl Acad Sci USA 93, 14559-63 (1996).
Molecular Weight 838.6
Sequence (One-Letter Code) Ac-WEHD-AFC
Sequence (Three-Letter Code) Ac - Trp - Glu - His - Asp - AFC

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