This peptide is the H2-Kd-restricted epitope of Listeriolysin O (LLO), consisting of amino acids 91 to 99. LLO is necessary for Listeria monocytogenes to escape the vacuoles of host cells and enter the cytoplasm during infection. This fragment has been shown to be a potential vaccine candidate against L. monocytogenes by eliciting a CTL response in vivo.
Bahjat, K. et al. Infect Immun 74, 6387 (2006); Ballard, JD. et al. Proc Natl Acad Sci 93, 12531 (1996).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Gly - Tyr - Lys - Asp - Gly - Asn - Glu - Tyr - Ile - OH