The peptide is histone H3 (21-43) acetylated at Lys23, followed by biotinylated lysine. The acetylation of histone H3 occurs non-selectively in Lys14 or Lys23. Lysine acetylation of histone H3 is related to transcription activation. When the peptide purity is greater than 95%, the peptide is dissolved in distilled water at a concentration of 1 mg/ml, and lyophilized again into a powder form.
Garcia, B. et al. Nat Methods 4, 487 (2007); Grant, P. et al. J Biol Chem 274, 5895 (1999).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Thr - Lys(Ac) - Ala - Ala - Arg - Lys - Ser - Ala - Pro - Ala - Thr - Gly - Gly - Val - Lys - Lys - Pro - His - Arg - Tyr - Arg - Pro - Gly - Gly - Lys(Biotin) - OH