| Product Name | [Lys(Ac)9]-Histone H3 (1-24), H3K9(Ac) |
| Purity | HPLC>95% |
| Description | The histone 3 peptide is acetylated at position 9 of the lysine residue. In xenogeneic glioblastomas expressing O6-methylguanine DNA methyltransferase (MGMT), the increase in H3K9-ac was observed to be related to histone acetylation and up-regulation of MGMT, thus revealing chromatin-mediated The mechanism of up-regulation of MGMT may guide epigenetic therapy to influence the development mechanism of drug resistance in glioblastoma. |
| Storage | -20°C |
| References | Kitange GJ. et al. Clin Can Res. 18:4070 (2012) |
| Molecular Weight | 2597 |
| Sequence (One-Letter Code) | ARTKQTAR-K(Ac)-STGGKAPRKQLATKA |
| Sequence (Three-Letter Code) | H - Ala - Arg - Thr - Lys - Gln - Thr - Ala - Arg - Lys(Ac) - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys - Gln - Leu - Ala - Thr - Lys - Ala - OH |
[Lys(Ac)9]-Histone H3 (1-24), H3K9(Ac)Admin2021-01-12T06:28:23+00:00
