This peptide is histone 3, amino acid residues 21 to 44. It is dimethylated at Lys27 and monomethylated at Lys36, followed by biotinylated lysine. Histone methylation plays an important role in the regulation of chromatin structure and function.
Jung, HR. et al. Mol Cell Proteomics 9, 838 (2010).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Thr - Lys - Ala - Ala - Arg - Lys(Me2) - Ser - Ala - Pro - Ala - Thr - Gly - Gly - Val - Lys(Me1) - Lys - Pro - His - Arg - Tyr - Arg - Pro - Gly - Gly - Lys(Biotin) - OH