This peptide is trimethylated at lysine 79 from amino acid residues 73 to 83 of histone H3. Histone lysine methylation plays a role in transcriptional regulation. H3K79 can be methylated by Dot1. Methyltransferase related peptides: histone H3 (73-83), [Lys(Ac)79]-histone H3(73-83), H3K79(Ac), [Lys )79]-Histone H3 (73-83), H3K79 (Biotin)
Bheda, P. et al. PNAS 109, E916 (2012).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Glu - Ile - Ala - Gln - Asp - Phe - Lys(Me3) - Thr - Asp - Leu - Arg - OH