This is the 92 to 106 amino acid fragment of myelin oligodendrocyte glycoprotein (MOG). MOG (92-106)-induced experimental autoimmune encephalomyelitis mice produced extensive B cell responses to secondary myelin antigens. Although this MOG peptide only induces a weak T cell response, the autoimmune response induced by MOG is very serious. This peptide is brain-derived in SJL mice, DA rats and rhesus monkeys.
Bischof, F. et al. J. Immunol. 173, 600 (2004).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Asp - Glu - Gly - Gly - Tyr - Thr - Cys - Phe - Phe - Arg - Asp - His - Ser - Tyr - Gln - OH