This is Spexin-2 (53-70), which is a non-amidated form of the new peptide hormone. It is derived from the prohormone proNPQ and is very conserved in mammals. It is the main regulator of cardiovascular and renal function. After administering Spexin-2 to rats, it can reduce heart rate and increase urine flow rate
1. Gu L. et al. Peptides 71, 232-239 (2015).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
Phe - Ile - Ser - Asp - Gln - Ser - Arg - Arg - Lys - Asp - Leu - Ser - Asp - Arg - Pro - Leu - Pro - Glu - OH