| Product Name | [Trp63, 64]-C3a (63-77) |
| Purity | HPLC>95% |
| Description | This peptide, which is a C-terminal analogue of the complement factor C3a, acts as an agonist to the C3a receptor. It is derived from the fifteen C-terminal residues (6-77) of C3a. In in vitro studies, both C 3a and this peptide have been shown to selectively bind to C3aRs and induce degranulation of C3aR-transfeted RBL-2H3 cells. There was also a rapid, transient and concentration-dependent hypertensive response observed in rats when infused intravenously with C3a and this peptide. |
| Storage | -20°C |
| References | 1, Proctor LM et al. Intl Immunopharmacol. 9, 800-806 (2009). 2, Ames, R. et al. Immunopharmacol. 38, 87 (1997). |
| Molecular Weight | 1820.2 |
| Sequence (One-Letter Code) | WWGKKYRASKLGLAR |
| Sequence (Three-Letter Code) | H - Trp - Trp - Gly - Lys - Lys - Tyr - Arg - Ala - Ser - Lys - Leu - Gly - Leu - Ala - Arg - OH |
[Trp63, 64]-C3a (63-77)Admin2021-01-05T13:12:23+00:00
