Showed the highest inhibitory activity against the T cell line-tropic HIV-1 infection through its specific binding to a chemokine receptor CXCR4 (IC₅₀ = 0.18 ± 0.041 nM) and the strongest inhibitory effect on the binding of an anti-CXCR4 monoclonal antibody to CXCR4 (IC₅₀ = 2.3 ± 0.20 nM).
H.Tamamura et al., Biochem. Biophys. Res. Commun., 253, 877 (1998)